Figure 5From: Targeted epigenome editing of an endogenous locus with chromatin modifiers is not stably maintained Conclusions for the reprogramming of epigenetic states. (A) Individual stimuli (indicated by the purple arrow) can edit the epigenetic state and silence gene expression but the silenced state is not stable. (B) For stable epigenetic silencing, presumably multiple triggers or individual triggers lasting over longer times are needed.Back to article page