Figure 1
From: De novo identification of differentially methylated regions in the human genome
Effect size for VA vs SA, VA vs VAT comparisons. (a) Moderated t distribution of all 450K probes from the VA vs SA and VA vs VAT comparisons, derived from their respective limma top tables. (b) Log-scaled total width of DMRs called by BSmooth on the VA vs SA and VA vs VAT comparisons from WGBS data, for varying values of the |t| cutoff. DMR, differentially methylated region; SA, subcutaneous adipocyte; VA, visceral adipocyte; VAT, visceral adipose tissue; WGBS, whole-genome bisulfite sequencing.