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Figure 2 | Epigenetics & Chromatin

Figure 2

From: Transcription-coupled recruitment of human CHD1 and CHD2 influences chromatin accessibility and histone H3 and H3.3 occupancy at active chromatin regions

Figure 2

Recruitment of CHD1 and CHD2 at CpG island (CGI) promoters correlates with RNA polymerase II (Pol II) occupancy independently of micrococcal nuclease (MNase) sensitivity. Genes with CGI overlapping the transcription start sites (TSS) were organized into quintiles of ascending Pol II occupancy in K562 cells. The average MNase-seq signal, CHD1 and CHD2 occupancy was then plotted across the region from -2500 to +2500 bases from the annotated TSS. Light gray lines represent the bottom quintile, medium gray the second lowest quintile, dark gray the third quintile, black the fourth and red the fifth quintile of Pol II occupancy.

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Epigenetics & Chromatin

ISSN: 1756-8935