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Table 3 Ectopic CENP-A nucleosomes are stable octamers

From: CENP-A nucleosomes localize to transcription factor hotspots and subtelomeric sites in human cancer cells

  SW480 bulk chromatin (n) Recomb. H3 octamer (n) Recomb. CENP-A octamer (n) SW480 total CENP-A (n) SW480 ectopic CENP-A (n)
Height a (nm) 2.53 ± 0.26 (401) 2.32 ± 0.32 (57) 2.37 ± 0.34 (57) 2.17 ± 0.35 (546) 2.46 ± 0.40 (135)
Diameter b (nm) 13.8 ± 1.4 (401) 12.1 ± 1.4 (20) 10.6 ± 1.4 (20) 14.1 ± 2.9 (546) 14.5 ± 3.0 (135)
  1. AFM measurements of aheight and bdiameter data of ectopic versus centromeric or recombinant CENP-A nucleosomes provided as average ± standard deviation, with number of particles measured indicated in parenthesis. On average, each type of experiment has three replicates.