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Table 1 CENP-A, ATRX and DAXX are overexpressed in colorectal cell lines

From: CENP-A nucleosomes localize to transcription factor hotspots and subtelomeric sites in human cancer cells

Cell Line

CENP-A a

HJURP a

ATRX a

DAXX a

Normal colon

1

1

1

1

DLD1

0.57 ± 0.12

2.19 ± 0.73

9.40 ± 1.25

1.22 ± 0.12

HeLa

1.26 ± 0.09

1.55 ± 0.55

5.22 ± 0.14

2.07 ± 0.07

HCT116

1.32 ± 0.10

2.89 ± 0.95

13.94 ± 4.01

3.66 ± 0.15

HT29

1.35 ± 0.11

4.69 ± 1.80

19.05 ± 8.10

3.18 ± 0.15

SW480

1.75 ± 0.23

1.24 ± 0.25

22.40 ± 3.91

2.80 ± 0.22

  1. aFold-changes in each protein (CENP-A, HJURP, ATRX and DAXX) were calculated as the ratio of that protein/H4 divided by ratio of the same protein/H4 in normal colon cells. Data represents 3 replicates.