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Table 2 Extent of homo- vs. hemimethylation at CpG dyads in densely methylated subclones

From: Analysis of DNA methylation acquisition at the imprinted Dlk1 locus reveals asymmetry at CpG dyads

 

BxC9C12 adult liver

C9C12xB adult liver

 

Paternal

Maternal

Paternal

Maternal

Independent subclones analyzed (n)

10

9

15

21

Subclones with >65% methylation (n)

8

5

8

0

Methylated dyads (n)

95

65

109

N/A

Homomethylated dyads (n,%)

89 (93.7%)

54 (83.1%)

92 (84.4%)

N/A

Hemimethylated dyads (n,%)

6 (6.3%)

11 (16.9%)

17 (15.6%)

N/A