Skip to main content
Figure 8 | Epigenetics & Chromatin

Figure 8

From: Three-dimensional super-resolution microscopy of the inactive X chromosome territory reveals a collapse of its active nuclear compartment harboring distinct Xist RNA foci

Figure 8

Model views of Barr body architecture and general CT architecture. (A) 3D-SIM section through a DAPI-stained C2C12 nucleus with framed areas representing a typical part, both from the Xi and from a neighboring, transcriptionally competent CT. (B) To scale scheme of the topographical relationships between chromatin and different targets addressed in this study at 3D-SIM resolution. (C) Hypothetical model views of both Xi and autosomal chromatin organization with yet unreached resolution approaching the size of individual nucleosomes. For a detailed description of this figure, refer to the discussion in the main text. 3D-SIM, three-dimensional structured illumination microscopy; CT, chromosome territory; DAPI, 4',6-diamidino-2-phenylindole; Xi, inactive X chromosome.

Back to article page