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Figure 2 | Epigenetics & Chromatin

Figure 2

From: Chd1 co-localizes with early transcription elongation factors independently of H3K36 methylation and releases stalled RNA polymerase II at introns

Figure 2

Chd1 co-localizes with early elongating RNAPII. (A) In a wide view, Chd1 occupancy appears similar to both RNAPII Ser 5-P and Ser 2-P occupancy. (B) Close-up views of highly expressed genes reveal that Chd1 occupancy appears similar to the occupancy profile of RNAPII Ser 5-P, but not Ser 2-P. (C) The peak shapes of Chd1 are quantitatively compared with those of either RNAPII Ser 5-P or Ser 2-P using shapeDiff. Histogram of correlation coefficients shows that RNAPII Ser 5-P has high correlation with Chd1 occupancy, whereas RNAPII Ser 2-P has little correlation with Chd1 on a genome wide scale.

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