Figure 2
From: Mechanistic stochastic model of histone modification pattern formation
Example simulation of the 1D diffusion transferase mechanism. Over a 200-s period, the modification state of each nucleosome is recorded with the acetylated state in green and methylated state in red. The initiation site is situated at position 25, this is the only point of influx of the methyltransferase. The first 5 s of the simulation are shown in higher detail. Parameters used in this simulation are given in Table 1 with k on = 2.4 s-1 .