Skip to main content
Figure 2 | Epigenetics & Chromatin

Figure 2

From: G9a/GLP-dependent H3K9me2 patterning alters chromatin structure at CpG islands in hematopoietic progenitors

Figure 2

H3K9me2 is nucleated at CpG-island-like regions across the genome. Measuring the (A) GC% and (B) CpG score at H3K9me2 peaks overlapping and non-overlapping CGIs and comparing these to randomly chosen regions indicates that H3K9me2 peaks have GC content similar to CGIs, even if they are not considered “classical” CGIs. (C) Scatter plot of FAIRE signals at RefSeq promoter and Orphan CGIs for UNC0638- and DMSO-treated samples. A general increase in chromatin accessibility upon UNC0638 treatment is observed at both Promoter and Orphan CGIs.

Back to article page