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Table 1 Expression levels of selected sub-telomere genes of the ring17 patient, significantly deregulated compared with controls

From: Telomere shortening and telomere position effect in mild ring 17 syndrome

Gene symbol Gene name Fold change P
   (standard deviation)  
17p: 1 to 1,500,000
RPH3AL Rabphilin 3A-like (without C2 domains) −2.99 (0.15) 0.001
FAM57A Family with sequence similarity 57, member A −1.61 (0.04) 0.002
GEMIN4 Gem (nuclear organelle) associated protein 4 −1.70 (0.03) 0.001
RNMTL1 RNA methyltransferase like 1 1.13 (0.03) 0.018
NXN Nucleoredoxin −1.87 (0.05) 0.001
YWHAE Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide −1.04 (0.01) <0.001
MYO1C Myosin IC −1.15 (0.01) 0.001
17q: 79,695,210 to- 81,195,210
ARHGDIA ρ GDP dissociation inhibitor α −1.67 (0.02) <0.001
SIRT7 Sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) −1.09 (0.01) 0.010
NARF Nuclear prelamin A recognition factor −1.86 (0.02) <0.001
FOXK2 Forkhead box K2 −1.44 (0.07) 0.008
FN3K Fructosamine 3 kinase −2.18 (0.06) <0.001
  1. Genes are listed from the telomere down to 1.5 Mb on the p arm and from the position 79,695,210 of the q arm up to the telomere. The expression values are reported as the mean fold change of three replicates.