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Table 4 Multiple linear regression models in which technical versus biological components of transcriptional noise are separately analyzed

From: DNA methylation and transcriptional noise

Predictors Estimate of β t value Significance VIF
Model 1a     
Intercept 1.201 14.12 <10-4  
Expression −0.442 −78.19 <10-4 1.06
Gene body methylation −0.797 −7.33 <10-4 1.07
Promoter methylation 0.613 6.17 <10-4 1.06
Adjusted R2     0.53
Model 2b     
Intercept 0.769 11.157 <10-4  
Expression −0.337 −61.354 <10-4 3.39
Gene body methylation −0.566 −9.463 <10-4 1.10
Promoter methylation 0.431 7.969 <10-4 1.07
Technical noise 0.608 32.467 <10-4 3.30
Adjusted R2     0.82
  1. aModel 1 used CV calculated from biological component as response variable.
  2. bModel 2 used CV calculated from total variation as response variable.
  3. CV, coefficient of variation; VIF, variance inflation factor.