DNA methylation and transcriptional noise

Table 2 Multiple linear regression models explaining variation of transcriptional noise in different tissues

Predictors	Estimate of β	t value	Significance	VIF
Brain
Intercept	1.47	19.57	<0.0001
Expression abundance	−0.59	−180.78	<0.0001	1.12
Gene body methylation¹	−0.19	−3.16	0.0016	2.34
TE methylation	−0.23	−5.78	<0.0001	1.44
Promoter methylation	0.18	4.54	<0.0001	1.28
Log (gene length)^a	0.015	1.54	0.12	2.10
Adjusted R²				0.87
Blood
Intercept	1.87	28.65	<0.0001
Expression abundance	−0.55	−236.94	<0.0001	1.11
Gene body methylation¹	−0.28	−4.95	<0.0001	1.93
TE methylation	−0.22	−5.77	<0.0001	1.43
Promoter methylation	0.27	6.88	<0.0001	1.28
Log (gene length)^a	−0.025	−3.19	0.0014	1.81
Adjusted R²				0.92

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