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Figure 1 | Epigenetics & Chromatin

Figure 1

From: Vertebrate GAGA factor associated insulator elements demarcate homeotic genes in the HOX clusters

Figure 1

ChIP-on-chip array reveals histone-free regions in the murine Hox clusters. Screenshots from the histone H3 array data visualized using the UCSC genome browser [43] showing normalized log ratios (NLRs) of probes (y axis) at the Hox clusters. Large stretches of unenriched probes showing negative NLR values are highlighted by boxed regions. The genomic scale bar is indicated at the top. A map of all the HFRs (green boxes) within each cluster identified by bioinformatics analysis is presented at the bottom in the context of the genic regions (blue boxes with transcriptional orientation indicated; the large intronic regions of Hoxa3 and Hoxd3 genes have been omitted for clarity). Red boxes correspond to locations of noncoding transcripts (multiple transcripts mapping to same location are clubbed for clarity) and dark green boxes correspond to CpG islands.

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