Mitotic bookmarking by transcription factors

Table 2 Factors that are at least partially bound to mitotic chromosomes

Basal transcription machinery	Sequence-specific transcription factors	Transcription cofactors	Chromatin writers	Chromatin readers
TBP^*[19, 49, 54, 61, 75, 79, 82, 90]	SRF (p67) [99]	MEN1 (Menin) [19]	MLL^*[19, 100]	L3MBTL1 (L(3)mbt)
BRF1 (TFIIIB) [75]	TFAP2A (AP-2) [47]	RBBP5[19]	ASH2L[19]	[101]
TFIIIC2[75]	HSF2[53]	BMI1^* (Psc) [21, 76, 101–103]	RING1[21, 102]	BRD2[104]
	NFE2 (p45) [18]	TLE1^* (Groucho) [59, 105]	SUV39H1^*[106, 107]	BRD4^*[23–25, 27, 104]
	RUNX2[26, 30, 33, 59]	HMGB1^* (HMG1) [20, 108, 109]		CBX8^* (Polycomb) [21, 76]
	HNF1B (HNF1-β) [95]			CBX4 (Pc2) [102]
	FOXI1[110]
	FOXA1[20]
	GATA1* [16, 18]
	GATA4[20]
	CEBPA^* (C/EBP α) [20, 47]
	CEBPB (C/EBP β) [111]
	UBTF (UBF-1) [33]
	DR1 (NC2) [61]
	Dm Trl (GAGA factor) [35, 112]
	Dm Psq (Pipsqueak) [112]
	At VRN1[113]

Factors that have been reported to remain bound to mitotic chromosomes are shown and references are provided as in Table 1. Factors that lack human homologues are indicated by the species-specific gene name (Dm, Drosophila melanogaster; At, Arabidopsis thaliana). ^*Indicates conflicting reports, which may be due to differences in species, cell type, and/or techniques by which the factor was examined.

ISSN: 1756-8935