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Figure 4 | Epigenetics & Chromatin

Figure 4

From: A permissive chromatin structure is adopted prior to site-specific DNA demethylation of developmentally expressed genes involved in macronuclear differentiation

Figure 4

Inhibition of histone acetyltransferase and histone deacetylase. (A, B) Effect of histone acetyl transferase inhibitor C646 and histone deacetylase inhibitor TSA on the DNA methylation pattern of mdp1 (A) and mdp2 (B). (C) The effect of histone deacetylase inhibitor C646 on the expression of these nanochromosomes during sexual reproduction was analyzed by qPCR. In both cases a dramatic decline in expression is observed after treatment with C646.

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Epigenetics & Chromatin

ISSN: 1756-8935