Position of methylated domains in the sperm genome. (A) Examples of typical CXXC-affinity purification followed by deep sequencing (CAP-seq) profiles of 30 kb. Read densities (gray) are as follows: KHC2: 2,755,136 to 2,785,136 (top), KHC6: 1,048,981 to 1,078,981 (middle) and KHC9: 4,508,000 to 4,538,000 (bottom). Genes (KH2010) are annotated below the CAP-seq profiles in blue. Methylated domains are indicated by green bars. (B) Methylated genes in sperm (genes with methylated domains with more than 80% overlap) were aligned at the 5′ end (left dashed line) or the 3′ end (right dashed line), and the total number of methylated domains are plotted.