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Table 2 Expression levels of epidermis genes and DNA methylation factors

From: Aging is associated with highly defined epigenetic changes in the human epidermis

Gene group Gene Expression (young) Expression (old) q value
Epidermis keratins KRT1 14719.2 14954.2 1.0
  KRT2 7291.7 6154.7 1.0
  KRT5 5860.6 5247.7 1.0
  KRT10 26232.1 23374.7 1.0
  KRT14 5665.0 4430.4 1.0
  KRT15 382.1 400.1 1.0
Epidermis structural factors LOR 613.4 427.3 1.0
  FLG 558.1 501.3 1.0
  FLG2 322.5 336.5 1.0
Fibroblast markers (dermis) VIM 41.0 54.0 1.0
  DES <0.1 <0.1 1.0
DNA methylation factors DNMT1 9.5 7.3 1.0
  DNMT3A 1.5 1.2 1.0
  DNMT3B 1.4 1.5 1.0
  DNMT3L <0.1 <0.1 1.0
  UHRF1 1.3 1.2 1.0
  TET1 0.1 0.1 1.0
  TET2 8.4 6.9 1.0
  TET3 18.8 14 1.0
  1. Expression levels represent FPKM values [21]; levels >1 indicate expression; q values were calculated by DESeq [20].