Aging is associated with highly defined epigenetic changes in the human epidermis

Table 1 Sequencing data

Sample	Age range	Sequencing	Number of read pairs	Mapping efficiency	Coverage	Conversion rate
Young (n = 5)	18–24	Transcriptome	225,332,853	89%	500x	n. d.
		Methylome	344,185,333	69%	11.3x	99.84%
Old (n = 5)	70–75	Transcriptome	221,387,474	88%	500x	n. d.
		Methylome	334,873,828	74%	11.9x	99.88%

Coverage indicates the average strand-specific genome or transcriptome coverage. Bisulfite conversion rates were determined by analyzing the conversion rates of co-purified mitochondrial genomes that were considered as unmethylated. Mitochondrial genome coverages were 1319x (young) and 1643x (old), respectively. n. d.: not determined.

ISSN: 1756-8935