Within-individual correlation in DNA methylation between tissues. (A) Relation between differences within two individuals in blood versus one other tissue. (B) Venn diagram of the number of CpGs sites that are correlated between blood and one or more tissues. (C) Top: A variably methylated CpG site in muscle that is correlated with DNA methylation in blood. Bottom: A variably methylated CpG site that is correlated across all tissues likely due to the influence of SNPs. SC, subcutaneous; SNP, single nucleotide polymorphism.