Figure 3From: Constitutional trisomy 8 mosaicism as a model for epigenetic studies of aneuploidyPromoter-specific methylation and hydroxymethylation on the X chromosome in the female culture is higher and lower, respectively, compared with the male cultures. A rank plot of median-centered promoter-specific methylation and hydroxymethylation log2 levels on the X chromosome reveals that the female reference culture generally displays higher levels (P <0.05; t-test) of methylation compared with (A) the average levels in the male cultures and (B) lower levels (P <0.05; t-test) of hydroxymethylation compared with the male cultures.Back to article page