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Figure 2 | Epigenetics & Chromatin

Figure 2

From: Constitutional trisomy 8 mosaicism as a model for epigenetic studies of aneuploidy

Figure 2

Promoter-specific hydroxymethylation levels on chromosome 8 are significantly lower in the trisomy 8 compared with the disomy 8/reference cultures. The levels of average promoter-specific hydroxymethylation on chr8 in the trisomy 8 and in the disomy 8 and reference cultures combined were log2-converted, median-centered, and plotted against genomic positions. Significantly lower levels (P < 0.05; t-test) were observed in the trisomy 8 cultures. chr8, chromosome 8.

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