Figure 2From: Constitutional trisomy 8 mosaicism as a model for epigenetic studies of aneuploidyPromoter-specific hydroxymethylation levels on chromosome 8 are significantly lower in the trisomy 8 compared with the disomy 8/reference cultures. The levels of average promoter-specific hydroxymethylation on chr8 in the trisomy 8 and in the disomy 8 and reference cultures combined were log2-converted, median-centered, and plotted against genomic positions. Significantly lower levels (P < 0.05; t-test) were observed in the trisomy 8 cultures. chr8, chromosome 8.Back to article page