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Table 3 Rescue of CTCF-deficient ES cells by exogenously introduced GFP-CTCF(L)

From: The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner

Species Construct Deletion in ES cells** Partial deletion in ES cells** No deletion in ES cells** Functional CTCF substitution
N.a.* GFP-CRE 0% (0/65) 28% (18/65) 72% (47/65) No
Mouse GFPCTCFL- 0% (0/18) 50% (9/18) 50% (9/18) No
Mouse CTCFGFP- CRE 83% (19/23) 0% (0/23) 17% (4/23) Yes
Mouse GFPCTCF- CRE 95% (40/42) 2% (1/42) 2% (1/42) Yes
Chicken CTCFYFP- CRE 90% (37/41) 2% (1/41) 7% (3/41) Yes
  1. *: Not applicable.
  2. **: Percentage and number of clones (between brackets) in which the conditional CTCF alleles were deleted, partially deleted or not deleted are shown.