Patterns of allele-specific expression (ASE), histone modification (ASHM), and methylation (ASM) along chromosomes 15 (right) and 17 (left). Sites of ASE are plotted in the outer blue circle, ASHM in the middle red circle, and ASM in the inner green plot. Significant sites are shaded darker in each case. Points correspond to –log( P) values in each plot except for ASM sites on the negative reference strand, where log( P) is plotted (purple points in the inner green plot). Known imprinted loci and indel regions associated with developmental disorders are indicated by orange and blue boxes, respectively, at the centre of the plot. Names of regions associated with developmental disorders within 250 kb of a site of ASHM are shown in red along with positions (in Mb) around the outside of the figure .