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Table 1 Yeast and mammalian ATP-dependent chromatin remodeling proteins and complexes implicated in the DDR.

From: ATP-dependent chromatin remodeling in the DNA-damage response

Family Complex ATPase Additional subunits Species Ref
SWI/SNF SWI/SNF Snf2 Swi3, Snf12, Arp7, Arp9, Snf11, Snf5, Snf6, Swi1, Swp82, Taf14 Yeast [157]
  RSC Sth1 Rsc1-4, Rsc6, Rsc8-, Rsc9, Rsc30, Rsc58, Rsc7, Arp7, Arp9, Sfh1, Htl1, Ldb7, Rtt102 Yeast [157]
  BAF SMARCA4/BRG1, SMARCA2/BRM ARID1A, SMARCC2, SMARCC1, SMARCD1-3, SMARCE1, ACTL6A, SMARCB1/SNF5, BAF45a-d, BRD7, BRD9, ACTB Mammal [17, 157]
  PBAF SMARCA4/BRG1, SMARCA2/BRM ARID2, PBRM1, SMARCC2, SMARCC1, SMARCD1-3, SMARCE1, ACTL6A, SMARCB1/SNF5, BAF45, BRD7, BRD9, ACTB Mammal [157]
INO80 INO80 Ino80 Arp4, Arp5, Arp8, Act1, Rvb1, Rvb2, Taf14, Ies1-6, Nhp10 Yeast [158]
  SWR1 Swr1 Arp4, Arp6, Act1, Rvb1, Rvb2, Yaf9, Vps71, Vps72, Swc3-5, Swc7, Bdf1 Yeast [17, 158]
  INO80 INO80 RUVBL1, RUVBL2, ACTL6A, ACTR5/Arp5, ACTR8/Arp8, INO80B, INO80C, TFPT, NFRKB, MCRS1, INO80E, INO80D Mammal [17]
  TRRAP/Tip601 EP400/p400 RUVBL1, RUVBL2, KAT5/Tip60, ACTL6A, ACTB, YEATS4, DMAP1, VPS72, BRD8, MORF4L1, MORF4L2, MEAF6, C20orf20, EPC1, EPC2, ING3 Mammal [17]
CHD NuRD CHD3, CHD4 MBD2, MBD3, MTA1-3, HDAC1, HDAC2, RBBP7, RBBP4, GATAD2A, GATAD2B Mammal [17, 159]
   CHD22   Mammal [137]
ISWI ISWIa Isw1 Ioc3 Yeast [160]
  ISWIb Isw1 Ioc2, Ioc4 Yeast [160]
  ISW2 Isw2 Itc1, Dpb4, Dls1 Yeast [17, 160]
  ACF SMARCA5/hSNF2H BAZ1A/hACF1 Mammal [17, 160]
  CHRAC SMARCA5/hSNF2H BAZ1A/hACF1, CHRAC1, POLE3 Mammal [17, 160]
  WICH SMARCA5/hSNF2H BAZ1B/WSTF Human [17, 160]
  NURF SMARCA1/hSNF2L BPTF, RBBP7, RBBP4 Mammal [17, 160]
Uncategorized   Rad16   Yeast [48, 49]
   Rad26   Yeast [161]
   Rad5   Yeast [162]
   Rdh54   Yeast [163, 164]
   CHD1L/ALC1   Mammal [132, 133]
   ERCC6/CSB   Mammal [165]
   HLTF   Mammal [166, 167]
   RAD54L   Mammal [90, 168]
   RAD54B   Mammal [169–171]
   SHPRH   Mammal [167, 172]
   SMARCAL1   Mammal [173, 174]
  1. See main text for references in which the different ATP-dependent chromatin-remodeling complexes are implicated in the DNA-damage response.
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Epigenetics & Chromatin

ISSN: 1756-8935