Skip to main content
Figure 3 | Epigenetics & Chromatin

Figure 3

From: Lysine methyltransferase G9a is not required for DNMT3A/3B anchoring to methylated nucleosomes and maintenance of DNA methylation in somatic cells

Figure 3

Depletion of G9a does not impair maintenance of DNA methylation in somatic cells. (A) Western blot of nuclear extracts from HCT116 cells infected with either control (NS) shRNA or shRNAs against G9a (shG9a5 or shG9a7), prepared 14 days after infection. (B) The levels of DNA methylation at different loci in HCT116 cells infected with either control (NS) shRNA or shRNAs against G9a (shG9a5 or shG9a7) were measured through Ms-SNuPE 14 days after infection. Data represent mean and SEM of methylation levels measured at three independent CpG sites within each locus.

Back to article page