|
Average velocity (μm/s)
|
---|
|
HP1β
|
BMI1
|
TRF1
|
---|
Peripheral foci: control
|
0.034 ± 0.007
|
0.017 ± 0.003
|
0.024 ± 0.005
|
Peripheral foci: TSA
|
0.024 ± 0.011
|
0.012 ± 0.005
|
0.046 ± 0.012
|
Peripheral foci: actinomycin D
|
0.024 ± 0.003
|
0.016 ± 0.005
|
0.021 ± 0.015
|
Peripheral foci: vorinostat
|
0.020 ± 0.003
|
0.020 ± 0.007
|
0.026 ± 0.010
|
Central foci: control
|
0.036 ± 0.018
|
0.015 ± 0.003
|
0.021 ± 0.004
|
Central foci: TSA
|
0.028 ± 0.017
|
NA
|
0.050 ± 0.020
|
Central foci: actinomycin D
|
0.022 ± 0.003
|
0.013 ± 0.003
|
0.018 ± 0.003
|
Central foci: vorinostat
|
0.020 ± 0.004
|
0.017 ± 0.003
|
0.026 ± 0.010
|
Velocity mean: control
|
0.035 ± 0.012
|
0.016 ± 0.003
|
0.023 ± 0.005
|
Velocity mean: TSA
|
0.026 ± 0.014
|
-
|
0.047 ± 0.015
|
Velocity mean: actinomycin D
|
0.023 ± 0.003
|
0.015 ± 0.005
|
0.020 ± 0.010
|
Velocity mean: vorinostat
|
0.020 ± 0.004
|
0.018 ± 0.005
|
0.026 ± 0.010
|
- NA indicates that it was not possible to recognise centrally positioned foci using automated computer analysis.
- TSA = trichostatin A.