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Table 2 Average velocity of heterochromatin protein 1β (HP1β), B lymphoma Mo-MLV insertion region 1 (BMI1), and telomeric-repeat binding factor 1 (TRF1) foci

From: Heterogeneity in the kinetics of nuclear proteins and trajectories of substructures associated with heterochromatin

  Average velocity (μm/s)
  HP1β BMI1 TRF1
Peripheral foci: control 0.034 ± 0.007 0.017 ± 0.003 0.024 ± 0.005
Peripheral foci: TSA 0.024 ± 0.011 0.012 ± 0.005 0.046 ± 0.012
Peripheral foci: actinomycin D 0.024 ± 0.003 0.016 ± 0.005 0.021 ± 0.015
Peripheral foci: vorinostat 0.020 ± 0.003 0.020 ± 0.007 0.026 ± 0.010
Central foci: control 0.036 ± 0.018 0.015 ± 0.003 0.021 ± 0.004
Central foci: TSA 0.028 ± 0.017 NA 0.050 ± 0.020
Central foci: actinomycin D 0.022 ± 0.003 0.013 ± 0.003 0.018 ± 0.003
Central foci: vorinostat 0.020 ± 0.004 0.017 ± 0.003 0.026 ± 0.010
Velocity mean: control 0.035 ± 0.012 0.016 ± 0.003 0.023 ± 0.005
Velocity mean: TSA 0.026 ± 0.014 - 0.047 ± 0.015
Velocity mean: actinomycin D 0.023 ± 0.003 0.015 ± 0.005 0.020 ± 0.010
Velocity mean: vorinostat 0.020 ± 0.004 0.018 ± 0.005 0.026 ± 0.010
  1. NA indicates that it was not possible to recognise centrally positioned foci using automated computer analysis.
  2. TSA = trichostatin A.