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Figure 6 | Epigenetics & Chromatin

Figure 6

From: Myc and Miz-1 have coordinate genomic functions including targeting Hox genes in human embryonic stem cells

Figure 6

Myc represses expression of differentiation-associated including homeobox ( Hox ) genes, a function antagonized by Miz-1. (A) Confirmation of gene expression changes in c-myc knockdown (KD) embryonic stem (ES) cells, determined by gene expression array, by quantitative real-time (qRT)-PCR PCR. Real-time qRT-PCR of a series of differentiation-associated genes or metabolism related genes. Error bars are standard deviations. N = 3. (B) Venn diagram showing overlap among differentially expressed genes in Myc KD or Miz-1 KD ES cells. Gene ontology (GO) analysis of overlapping genes presented below the Venn diagram. P values are indicated.

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Epigenetics & Chromatin

ISSN: 1756-8935