Figure 4
From: The relationship between transcription initiation RNAs and CCCTC-binding factor (CTCF) localization
RNA polymerase II (RNAPII) response to the p21 (cyclin-dependent kinase inhibitor 1A gene, also known as CDKN1A ) CCCTC-binding factor (CTCF) proximal (cp)-transcription initiation (ti)RNA sponge. Active RNAPII enrichment sites in the p21 (CDKN1A) locus were determined by chromatin immunoprecipitation (ChIP). RNAPII levels are generally unaffected, although a modest increase in RNAPII activity downstream of the p21alt transcription start site was observed.