Skip to main content

Table 3 DNA methylation of identified DMRs in different tissues and gestational agesa

From: Genome-wide mapping of imprinted differentially methylated regions by DNA methylation profiling of human placentas from triploidies

Index Gene Chromosome Tissue-specificb Change in gestationc Stable non-tissue-specificd Known imprinted genese
1 DNAJC6 1 Yf Y N N
2 LASS2 1 Yf Y N N
3 PEX5 12 Yf Y N N
4 RASGRF1 15 Yf N N N
5 AKAP10 17 Yf N N N
6 AIFM2 10 Yf N N N
7 APC 5 Yf N N N
8 ARHGAP4 X Yf N N N
9 ARMC3 10 Yf N N N
10 C3orf62 3 Yf N N N
11 CD83 6 Yf N N N
12 CMTM3 16 Yf N N N
13 DNMT1 19 Yf N N N
14 G0S2 1 Yf N N N
15 GATA4 8 Yf N N N
16 LEP 7 Yf N N N
17 MCCC1 3 Yf N N N
18 NUDT12 5 Yf N N N
19 PCK2 14 Yf N N N
20 RHOBTB3 5 Yf N N N
21 SLC46A2 9 Yf N N N
22 SNCB 5 Yf N N N
23 SORD 15 Yf N N N
24 ST8SIA1 12 Yf N N N
25 TBX6 16 Yf N N N
26 TMEM17 2 Yf N N N
27 ZNF232 17 Yf N N N
28 ZNF396 18 Yf N N N
29 AK094715 6 Y Y N N
30 DIRAS3 1 Y Y N Y
31 CMTM8 3 Y Y N N
32 SEMA3B 3 Y Y N N
33 CDKN1C 11 Y N N Y
34 H19 11 Y N N Y
35 KCNQ1 11 Y N N Y
36 MEG3 14 Y N N Y
37 PEG10 7 Y N N Y
38 C10orf125 10 Y N N N
39 CCR10 17 Y N N N
40 CYP2W1 7 Y N N N
41 FIGNL1 7 Y N N N
42 IGFBP1 7 Y N N N
43 MOV10L1 22 Y N N N
44 P2RY6 11 Y N N N
45 PARP12 7 Y N N N
46 SAMD10 20 Y N N N
47 L3MBTL 20 N Y N Y
48 ACPL2 3 N Y N N
49 REEP6 19 N Y N N
50 GNAS(M) 20 N N Y Y
51 GNAS(P) 20 N N Y Y
52 GRB10 7 N N Y Y
53 MEST 7 N N Y Y
54 NAP1L5 4 N N Y Y
55 PEG3 19 N N Y Y
56 PLAGL1 6 N N Y Y
57 SGCE 7 N N Y Y
58 SNURF 15 N N Y Y
59 ZIM2 19 N N Y Y
60 ZNF597 16 N N Y Y
61 FAM50B 6 N N Y N
62 FGF12 3 N N Y N
63 IRF7 11 N N Y N
  1. aDMR, differentially methylated region; bmulticlass comparison of methylation level in brain, kidney, muscle, midgestation placenta and blood with FDR <0.1%; cMulticlass comparison of methylation level in early-gestation, midgestation and term placenta, FDR <0.1%; dDMRs with no statistically significant changes in methylation level in different tissues and gestational ages; eBased on the public databases (http://igc.otago.ac.nz/ and http://www.geneimprint.com/); fplacenta-specific methylation.