Figure 1

Unsupervised clustering of triploid and normal placentas with CHMs and blood samples demonstrates that each tissue type has a distinct methylation profile. Sample names are shown with labelling of corresponding tissue types. Samples were clustered by hierarchical clustering of β values based on 1-r (Illumina GenomeStudio software), where r represents the correlation coefficient between samples. Digynic triploids are indicated by red boxes, diandric triploids by blue boxes and normal placentas by green boxes.