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Table 1 Size and position of chromatin domains at neocentromeres.

From: A paucity of heterochromatin at functional human neocentromeres

Cell Line

Domain

Size (kb)

Coord (hg18) chromosome 13

P value

BBB

CENP-A major

89.7

101,901,496-101,991,165

<10-5*

BBB

CENP-A minor

19

102,140,584-102,159,277

 

BBB

Intervening

142

101,998,994-102,140,584

 

BBB

CENP-C major

89.7

101,901,496-101,991,165

<10-5

BBB

CENP-C minor

19

102,140,584-102,159,277

<10-5

BBB

H3K4me2

0.740

101,969,955-101,970,694

<10-5

BBB

H3K9me3

15

102,183,799-102,198,988

<2.5 × 10-5

BBB

HP1α

15

102,183,799-102,198,988

<5.6 × 10-5

BBB

HP1γ

15

102,183,799-102,198,988

<9.6 × 10-5

IMS13q

CENP-A major

90

96,511,130-96,601,103

<10-5

IMS13q

CENP-A minor

15

96,661,230-96,676,244

 

IMS13q

Intervening

60

96,601,103-96,661,230

 

IMS13q

H3K4me2

1.8

96,575,232-96,577,051

<10-5

IMS13q

H3K9me3

159.5

102,375,370-102,531,950

<10-5

CHOP13q

CENP-A major

74

70,735,337-70,809,172

<10-5

CHOP13q

CENP-A minor

10

70,872,442-70,883,219

 

CHOP13q

intervening

64

70,809,175-70,872,440

 

CHOP13q

H3K4me2

0.7

70,763,283-70,763,914

<10-5

  1. *CENP-A major, minor and intervening domains are from same CENP-A ChIP for each cell line, and therefore are determined using same p value.
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Epigenetics & Chromatin

ISSN: 1756-8935