Chromatin immunoprecipitation analyses of histone modifications in differentiated mouse embryonic stem (DmES) cell nuclei transplanted to Xenopus germinal vesicles. Histone methylations in the promoter or regulatory regions of Sox2 (a and b), Sall4 (c), Oct4 (d) and β-globin (e) in transplanted DmES nuclei were analysed. H3K4 me2 is shown in blue, H3K4 me3 in red and H3K27 me3 in light green. The Y axis is the fold enrichment of modified histone over non-modified histone H3. The X axis is incubation time after nuclear transfer.