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Table 2 Relative turnover of H3 and H4 modified peptides

From: Global turnover of histone post-translational modifications and variants in human cells

Peptide1,2

Relative turnover3

Epigenetic Function4,5

H3K4me1

0.7326

A [52]

H3K9me1

0.7029

A [52]

H3K9me2

0.5840

S [52]

H3K9me3

0.4104

S [52]

H3K9/K14ac1

1.1816

A [38]

H3K18/K23ac1

1.2919

A [38]

H3K18ac1K23ac1

1.6818

A [38]

H3K27me1

0.5929

A [52]

H3K27me2

0.4272

S [52]

H3K27me3

0.2679

S [52]

H3K36me1

0.8803

A [52]

H3K36me2

0.5669

A [53]

H3K56ac1

3.8155

A [38]

H3K79me1

0.6671

A [54]

H3K79me2

0.5661

A [54]

H4K5/K8/K12/K16ac1

1.1968

A [38]

H4K5/K8/K12/K16ac2

1.5118

A [38]

H4K5/K8/K12/K16ac3

1.6048

A [38]

H4K5K8K12K16ac4

1.5483

A [38]

H4K20me1

0.5884

A [52]

H4K20me2

0.2283

S [55]

H4K20me3

0.1459

S [56]

  1. 1me = Methyl
  2. 2ac = Acetyl
  3. 3Relative turnover, with respect to the relevant unmodified peptide, is determined for various modified forms of H3 and H4.
  4. 4A = active marks
  5. 5S = silent marks