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Table 2 Relative turnover of H3 and H4 modified peptides

From: Global turnover of histone post-translational modifications and variants in human cells

Peptide1,2 Relative turnover3 Epigenetic Function4,5
H3K4me1 0.7326 A [52]
H3K9me1 0.7029 A [52]
H3K9me2 0.5840 S [52]
H3K9me3 0.4104 S [52]
H3K9/K14ac1 1.1816 A [38]
H3K18/K23ac1 1.2919 A [38]
H3K18ac1K23ac1 1.6818 A [38]
H3K27me1 0.5929 A [52]
H3K27me2 0.4272 S [52]
H3K27me3 0.2679 S [52]
H3K36me1 0.8803 A [52]
H3K36me2 0.5669 A [53]
H3K56ac1 3.8155 A [38]
H3K79me1 0.6671 A [54]
H3K79me2 0.5661 A [54]
H4K5/K8/K12/K16ac1 1.1968 A [38]
H4K5/K8/K12/K16ac2 1.5118 A [38]
H4K5/K8/K12/K16ac3 1.6048 A [38]
H4K5K8K12K16ac4 1.5483 A [38]
H4K20me1 0.5884 A [52]
H4K20me2 0.2283 S [55]
H4K20me3 0.1459 S [56]
  1. 1me = Methyl
  2. 2ac = Acetyl
  3. 3Relative turnover, with respect to the relevant unmodified peptide, is determined for various modified forms of H3 and H4.
  4. 4A = active marks
  5. 5S = silent marks
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