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Figure 5 | Epigenetics & Chromatin

Figure 5

From: Global turnover of histone post-translational modifications and variants in human cells

Figure 5

Turnover of modified H4 peptides. Mass spectrometry spectra of the H4 triacetylated 4-16 peptide (H4K5K8K12K16ac3), unmodified 24-35 peptide (H4K31un) and dimethylated 20-23 peptide (H4K20me2) during the labeling time course. Isotopic distributions of peptides that were 12C614N2-lysine unlabeled (white circle) or 13C615N2-lysine labeled (gray circle) are denoted on the spectra. Note the intermediate isotopic distribution (one white circle + three gray circles) of the 4-16 peptide has three of its four lysines labeled with 13C615N2-lysine.

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