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Figure 8 | Epigenetics & Chromatin

Figure 8

From: Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation

Figure 8

Gene expression profiling in wild-type and dnBrg1 lenses (day E15.5). (A) Four biological triplicates (R1 through R4) of mouse lenses were analyzed by Affymetrix GeneChip arrays to identify a set of 6,828 individual genes significantly modulated between wild-type (WT) and Brg1DN lenses. Statistical filtering of array data was performed as described in Methods. (B) Differential expression of Smarca4 (Brg1) gene determined by the arrays and quantitative reverse transcriptase polymerase chain reaction (qRT-PCR).

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Epigenetics & Chromatin

ISSN: 1756-8935