Figure 6

Aberrant lens fiber cell organization in the dnBrg1 transgenic mouse. Absence of "Y" suture formation (compare A and B) and ball-and-socket structure (compare C and E with D and F) revealed by scanning electron microscopy (SEM) suggested abnormal fiber cell differentiation in the transgenic mouse (age 3 mo). Altered fiber cell widths as well as a disturbed fiber cell organization pattern are shown at higher magnifications (C-F). Scale bars, 0.5 mm (A-B); 20 μm (C-D); 5 μm (E-F).