Disruption of fiber cell nuclei degradation in embryonic and postnatal dnBrg1 transgenic lenses. Lens midsections from both wild-type and Brg1DN mice from embryonic day 15. 5 (A and B), embryonic day 17.5 (C-F) and postnatal day P7 (G-H) were stained with hematoxylin and eosin. Failure of fiber cell nuclei degradation (H, arrows) and organelle-free zone formation was observed in the transgenic mice from embryonic stage E17.5 and persisted in postnatal stages. Scale bar, 100 μm.