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Figure 5 | Epigenetics & Chromatin

Figure 5

From: Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation

Figure 5

Disruption of fiber cell nuclei degradation in embryonic and postnatal dnBrg1 transgenic lenses. Lens midsections from both wild-type and Brg1DN mice from embryonic day 15. 5 (A and B), embryonic day 17.5 (C-F) and postnatal day P7 (G-H) were stained with hematoxylin and eosin. Failure of fiber cell nuclei degradation (H, arrows) and organelle-free zone formation was observed in the transgenic mice from embryonic stage E17.5 and persisted in postnatal stages. Scale bar, 100 μm.

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Epigenetics & Chromatin

ISSN: 1756-8935