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Figure 14 | Epigenetics & Chromatin

Figure 14

From: Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation

Figure 14

Identification of commonly regulated genes in dnBrg1 lenses and Brg1 cKO eyes. (A) Venn diagram showing numbers of upregulated genes and/or transcripts found in dnBrg1 and Brg1 cKO models. (B) Venn diagram showing numbers of downregulated genes and/or transcripts found in dnBrg1 and Brg1 cKO models. The genes and/or transcripts included in this analysis (6,533 in dnBrg1, and 2,196 in Brg1 cKO, respectively) were selected by two parameters: Pavlidis template matching (PTM), P < 0.05, and fold change > 1.5 as described in Methods [68].

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Epigenetics & Chromatin

ISSN: 1756-8935