Identification of lenses commonly regulated in dnBrg1 , Hsf4-/-and Pax6+/-. (A) Venn diagram showing number of genes and/or transcripts regulated in dnBrg1, Hsf4-/-and Pax6+/-lenses. (B) A list of 22 genes regulated in all three systems. The genes were analyzed using the unsupervised hierarchical clustering described in Methods. Gene Expression Omnibus database accession numbers for dnBrg1, heat shock transcription factor 4 (Hsf4) and paired box gene 6 (Pax6) data are GSE22322, GSE22362 and GSE13244, respectively.