Figure 1

Distribution of average sequence conservation (expressed as seven-way phastCons) for the complete nucleosome datasets, 3,061 consistent nucleosomes and 1,099 inter-nucleosomal consistent nucleosome-free regions (NFRs). Average conservation was calculated as the sum of PhastCons values for a given region divided by its total length. (A) Genic regions partition (n = 5,770). Segments overlapping 5,770 yeast genes from Shivaswamy et al. [8] (42041 nucleosomes), Lee et al. [7] (31,739 nucleosomes), consistent nucleosomes (2,449 cases), consistent NFRs (879 cases). (B) Intergenic regions partition (5,442). Segments included in 5,442 yeast intergenic regions from Shivaswamy et al. [8] (7,002 nucleosomes), Lee et al. [7] (8,350 nucleosomes), consistent nucleosomes (612 cases), consistent NFRs (220 cases). Dotted horizontal lines correspond to the mean conservation of genic and intergenic regions respectively, calculated as the average over the sum of their lengths.