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Figure 5 | Epigenetics & Chromatin

Figure 5

From: Menin and RNF20 recruitment is associated with dynamic histone modifications that regulate signal transducer and activator of transcription 1 (STAT1)-activated transcription of the interferon regulatory factor 1 gene (IRF1)

Figure 5

H2B monoubiquitination is dynamic during interferon regulatory factor 1 gene ( IRF1 ) induction. Chromatin immunoprecipitation (ChIP), using ubH2B antibody, of 2fTGH cells (a) or U3A cells (b) treated with interferon (IFN)γ for 30 min and collected after the various time points. IgG served as the negative control. Locations of quantitative PCR (Q-PCR) primers designed to span the entire locus of IRF1 are as in Figure 2h.

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Epigenetics & Chromatin

ISSN: 1756-8935