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Figure 2 | Epigenetics & Chromatin

Figure 2

From: An in vitro-identified high-affinity nucleosome-positioning signal is capable of transiently positioning a nucleosome in vivo

Figure 2

Nucleosome coverage and dyad positioning scores for nucleosomes in the promoter of human Factor IX (hFIX) constructs hFIX-Parent and hFIX-601 during time points of high expression and silencing. The dashed line at index = 1 represents the average expected nucleosome coverage at a given base pair. Vector base pair coordinate is plotted on the X-axis. Colored bars below each graph represent the span of the labeled vector DNA element. (a) Nucleosome coverage in the hFIX-Parent promoter at 3 days. (b) Nucleosome coverage in the hFIX-601 promoter at 3 days. (c) Nucleosome coverage in the hFIX-Parent promoter at 6 weeks. (d) Nucleosome coverage in the hFIX-601 promoter at 6 weeks. (e) Dyad positioning scores in the hFIX-Parent promoter at 3 days. (f) Dyad positioning scores in the hFIX-601 promoter at 3 days. (g) Dyad positioning scores in the hFIX-Parent promoter at 6 weeks. (h) Dyad positioning scores in the hFIX-601 promoter at 6 weeks.

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Epigenetics & Chromatin

ISSN: 1756-8935