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Figure 3 | Epigenetics & Chromatin

Figure 3

From: A role for non-coding Tsix transcription in partitioning chromatin domains within the mouse X-inactivation centre

Figure 3

Loss of H3K27 tri-methylation at the Xic during embryonic stem (ES) cell differentiation. (A) Map of Xic (see Figure 1A). (B-D) Extensive ChIP analysis of H3K27 trimethylation in (B) wild-type female ES cells (LF2), (C) wild-type male revertant cells (Ma1L), or (D) Tsix-truncated ES cells (Ma2L). ChIP experiments were performed on undifferentiated ES cells (black line) and after 2 and 4 days (orange and red lines, respectively) of differentiation with retinoic acid.

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