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Figure 2 | Epigenetics & Chromatin

Figure 2

From: The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis

Figure 2

The Magoh2 promoter is a direct target for Mll2 and a model example of trxG /PcG opposition (part 1). (A) Diagrams of the Magoh2 and Magoh genes, showing the exon structures, the positions of the CpG island promoters (as hatched lines around exon 1) and the PCR primer pairs for chromatin immunoprecipitation (ChIP) analysis. (B) Histogram of quantitative RT-PCR analysis of Magoh (dark green) and Magoh2 (light green) mRNA levels before and after addition of 4-hydroxy tamoxifen to Mll2F/F; Rosa26-CreERT2/+ cells.

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Epigenetics & Chromatin

ISSN: 1756-8935