Figure 2From: Yeast Sgf73/Ataxin-7 serves to anchor the deubiquitination module into both SAGA and Slik(SALSA) HAT complexesAnalysis of Ubp8 purifications in the absence of SGF73. A. Mudpit analysis of various Ubp8Tap purifications reveals the effect of the loss of SGF73 and SPT20 versus SGF11 on Ubp8-associated complexes. In the absence of SGF73, Ubp8 only co-purifies with other deubiquitination module components, Sus1 and Sgf11. The numbers represent total peptides obtained for each component. B. Ubp8-associated complexes purified in the absence of SGF73 and SPT20 lose the ability to deubiquitinate histone H2B in vitro.Back to article page