Figure 6From: The molecular basis for stability of heterochromatin-mediated silencing in mammalsIntegrating nuclear position, histone modifications and accessibility of the gene in maintaining heterochromatin-mediated gene silencing in vivo. Different 'epigenotypes' (right) are depicted alongside the expression status (left) of the affected gene - DNA methylation and locus inaccessibility were found to have the strongest correlation with stable gene silencing.Back to article page