Talking to chromatin: post-translational modulation of polycomb group function

Table 2 Site-specific polycomb sumoylation and ubiquitylation sites

Complex	Drosophila	Name	Alternative symbol	Accession no.	Total no. of amino acids	Modification site	Conservation in mouse	Refs
PRC2	Su(z)12	SUZ12		Q15022	739	K72 sumo	K74	[42]
						K73 sumo	K75	[42]
						K75 sumo	K77	[42]
PRC1	Pc	CBX4	HPC2	O00257	558	K492 sumo	K490	[38, 99, 100]
	Sce/dRING	Rnf2	RING1b	Q9CQJ4	336	K112 Ub	K112*	[7]
PhoRC	Pho	YY1		P25490	414	K288 sumo	K288	[101]

The table lists PTMs confirmed by mass spectrometric and/or mutational analysis.
Sumo = sumoylation site; Ub = ubiquitylation site.

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