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Table 1 Histone modifications associated with transcription and nucleotide excision repair.

From: Chromatin structure and DNA damage repair

PTM

Transcription

NER

H2AXS139ph/yH2AS129ph

?

+

yH2AS122ph

?

-

H2Aub

-

+

H3K9/K14ac

+

+

H3K79me

+

+

H3S10ph

+

-

H3T11ph

+

-

H4K20me

-

+

H3/H4ub

?

+

  1. ph = phosphorylation; ac = acetylation; me = methylation; ub = ubiquitination, '+' = upregulation or positive effect of the post-translational modification (PTM), '-' = downregulation or negative effect of the PTM and '?' = unknown function.
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Epigenetics & Chromatin

ISSN: 1756-8935