Figure 7

Bisulfite sequencing profile for L1Oc7(8). Graphical representation of individually sequenced bisulfite amplicons highlighting 10 CpG dinucleotide positions analyzed in this LINE1 element class. Open and closed circles indicate unmethylated and methylated CpGs, respectively. Some CpGs are absent in individual clones due sequence polymorphism in L1Oc7(8) copies. Taq I sites used for combined bisulfite restriction analysis assays are highlighted by black arrows.